Fund factsheetFundFacts API
Issuer iSharesFigures as of 2026-10-01Generated 4 Oct 2026

iShares Healthcare Innovation UCITS ETF USD (Acc)

IE00BYZK4776ETF

The Fund aims to achieve a return on your investment, through a combination of capital growth and income on the Fund’s assets, which reflects the return of the STOXX Global Breakthrough Healthcare Index, the Fund’s benchmark index (the Index) The Fund is passively managed, and aims to invest in equity securities (e.g. shares) that, so far as possible and practicable, make up the Index.

Growth of 100

10015020020182020202220242026
Fund212STOXX GLOBAL BREAKTHROUGH HEALTHCARE (Net)216
2016-09 → 2026-10 · rebased to 100

Key facts

TER0.40%
Fund sizeUSD 1.5bn
Inception2016-09-08
Holdings200
CurrencyUSD
DistributionAccumulating

Top holdings

  1. 01MODERNA4.89%
  2. 02NATERA2.27%
  3. 03ILLUMINA INC2.05%
  4. 04GENMAB1.73%
  5. 05IQVIA HOLDINGS1.73%
  6. 06REVVITY1.71%
  7. 07GUARDANT HEALTH1.66%
  8. 08AGILENT TECHNOLOGIES INC1.52%
  9. 09ROIVANT SCIENCES LTD1.51%
  10. 10CELLTRION1.49%

Sectors

98%Health Care
  • Health Care98.0%
  • Information Technology1.1%
  • Industrials0.5%
  • Real Estate0.2%

Countries

  1. United States71.5%
  2. Switzerland5.1%
  3. Japan4.4%
  4. Korea (South)3.7%
  5. Other2.9%
  6. Denmark2.6%
  7. Belgium2.3%
  8. Germany1.8%
  9. United Kingdom1.6%
  10. China1.4%

Asset allocation

100%Equity
  • Equity99.8%
  • Cash0.3%
  • Cash Collateral and Margins0.0%

Risk & profile

1
2
3
4
5
6
7
Lower risk · lower rewardHigher risk · higher reward
Global Health Care Equity
RiskMediumValuationGrowthConcentrationDiversifiedRegionGlobal · United States tiltSectorHealth Care

Calendar-year returns

+52.1%2020−6.0%2021−23.6%2022+2.1%2023+1.4%2024+18.5%2025
Fund STOXX GLOBAL BREAKTHROUGH HEALTHCARE (Net)

Annualised returns

PeriodFundIndexDiff
1 Year+26.57%+26.78%−0.21%
3 Years p.a.+17.04%+17.22%−0.18%
5 Years p.a.+1.33%+1.54%−0.21%
10 Years p.a.+7.78%+8.00%−0.22%
Since Inception+7.74%+7.96%−0.22%

Risk & valuation metrics

Volatility 3y16.51%
Sharpe 3y0.77
Max drawdown-18.4%
P/E ratio25.1x

Figures as of 2026-10-01. Data from FundFacts API; not investment advice.